INKO Seoul Ampule No. 03

PDRN Intensive
Repair

An intensive repair ampule designed to support visible recovery, deep hydration, and a healthier regenerated glow. PDRN is known as a purified salmon-derived DNA fragment ingredient, making it a strong fit for regenerative medicine-inspired skin care and advanced recovery-focused treatments.

PDRN Salmon-derived DNA fragments Purified salmon sperm DNA-derived PDRN Regenerative medicine Bio stimulators Microneedling protocol Skin density support Deep hydration Clinically approved
PDRN intensive repair ingredient visual
— What is it?

A salmon-derived repair ampule for depleted, fragile, dry, or stressed-looking skin.

PDRN, also known as polydeoxyribonucleotide, is a purified DNA-fragment ingredient commonly derived from salmon DNA, including purified salmon sperm DNA sources used in regenerative medicine research. In aesthetic skin care, salmon-derived PDRN is used to support visible repair, hydration, skin density, and overall skin-quality improvement. This ampule is ideal for skin that looks depleted, fragile, dry, stressed, or less bouncy. PDRN is a salmon-derived DNA-fragment ingredient used for visible repair, hydration, skin density, and recovery support.

Repair-support care

Helps skin look healthier, calmer, and more resilient when it appears tired, weakened, or slower to return to a comfortable-looking state. Helps tired or weakened skin look calmer, healthier, and more resilient.

Salmon-derived regenerative DNA support

PDRN is often described as a purified salmon DNA fragment ingredient, giving the ampule a strong regenerative medicine-inspired story for visible recovery and skin-quality support. Salmon DNA support for recovery and skin quality.

Collagen-looking firmness

Pairs well with renewal-focused treatments for smoother, firmer-looking skin quality. Supports smoother, firmer-looking skin quality.

Deep hydration and density

Best presented as a skin-density, hydration, and recovery-support ampule within the INKO treatment protocol. Supports hydration, density, and recovery-focused care.

— How this ingredient works

A repair‑signal recovery pathway.

PDRN supports intensive repair by working through regenerative medicine-inspired skin recovery logic: repair signaling, fibroblast-support care, matrix renewal, hydration comfort, and denser-looking skin quality.

Why skin looks depleted

Stress, dryness, and weak recovery

Skin can look fragile, rough, thin, or tired when its surface barrier is stressed and the deeper repair environment appears less active or less resilient.

repair pathway
Why PDRN helps

Recovery-signal support

PDRN is a purified salmon-derived DNA fragment ingredient associated with repair-support pathways, helping skin look calmer, stronger, and more regenerated.

01

DNA-fragment logic

PDRN provides purified DNA fragments that can be broken down into nucleotide building blocks, supporting the skin’s natural repair process when the surface looks weakened, stressed, or depleted.

02

Repair-signal logic

When skin is stressed, it needs energy and raw materials to restore a healthier surface. PDRN supports this recovery environment, helping skin look calmer, stronger, and more resilient.

03

Fibroblast-support logic

Fibroblasts help create collagen and extracellular matrix support. PDRN is associated with this repair pathway, helping skin look firmer, denser, smoother, and more elastic.

04

Hydration-comfort logic

Repair-focused skin care works better when the surface feels comfortable. PDRN helps position the skin as smoother, softer, and less depleted.

05

Density-glow logic

When recovery, hydration, and matrix support look improved, the skin appears more supple, more elastic, and naturally glowier.

Why it suits repair care

Repair care is not only about moisture. Depleted-looking skin also needs support for recovery signals, skin density, barrier comfort, and smoother texture.

Repair cycle support

PDRN supports the skin’s repair cycle by helping create a better recovery environment for barrier comfort, matrix quality, hydration, and smoother regenerated-looking skin.

In short: PDRN is good for intensive repair because it supports regenerative medicine-inspired repair signaling, fibroblast-related skin matrix quality, hydration comfort, and denser, smoother, more resilient-looking skin.

— What is it good for?

Recommended for skin that needs repair, hydration, firmness, and visible recovery support.

This ampule is ideal when the goal is a refined repair-focused glow with support for resilience, skin density, deep hydration, and healthier-looking recovery.

1
Post-treatment recovery support Supports skin that looks stressed or depleted after travel, dryness, breakouts, or aesthetic treatments.
2
Regenerative skin-quality care A refined option for repair, resilience, and long-term skin quality.
3
Skin density improvement A good match for skin that appears thin, tired, or less elastic.
4
Visible repair support Useful for protocols focused on comfort, hydration, and recovery-looking skin quality.
5
Deep hydration and glow Supports a more supple, hydrated, comfortable finish.

PDRN Ingredient Research

Salmon sperm DNA-derived PDRN, repair, regeneration, and skin-quality support
Squadrito et al., 2017

Pharmacological activity and regenerative use of salmon sperm DNA-derived PDRN

This review describes PDRN as a DNA-derived compound obtained from controlled purification and sterilization of salmon trout or chum salmon sperm DNA. It highlights PDRN’s tissue-repairing, anti-inflammatory, and regenerative activities, mainly linked to adenosine A2A receptor signaling.

View study
Galeano et al., 2021

PDRN and impaired skin wound-healing support

This review summarizes PDRN applications in skin regeneration, including support for cell migration, cell growth, angiogenesis, and inflammation modulation. The focus is impaired skin wound-healing models, making it useful for repair and recovery-support positioning.

View study
Research Summary PDRN research is widely associated with purified salmon sperm DNA-derived fragments, tissue-repair support, regenerative skin care, hydration, and collagen-related recovery pathways. This makes it a strong ingredient for intensive repair, skin-density support, post-treatment care, and a healthier regenerated glow.
— Delivery method

Microneedling(MTS)

A clearer way to help active ampoules reach the skin.

Microneedling creates controlled micro-channels on the skin surface. This helps selected ampoules absorb more effectively while encouraging the skin’s natural renewal response — useful when the goal is refined texture, pores, glow, and early-aging support.

01

Creates micro-channels

Creates tiny pathways on the skin’s surface, helping prepare the skin for more focused ampoule absorption.

02

Guides ampoule delivery

Allows the selected ampoule to reach the skin more effectively, targeting areas that need extra support.

03

Supports visible renewal

Encourages the skin’s natural renewal response, helping texture look smoother, fuller, and more refined over time.

Good to know: Temporary redness, warmth, sensitivity, or light flaking can occur after treatment. The depth, ampoule choice, and aftercare are adjusted according to the client’s skin condition and sensitivity.

Choose the right delivery method for your skin

PDRN can be applied through two INKO delivery methods: Microcurrent for gentle, non-invasive infusion, or microneedling for more targeted ingredient delivery and visible skin-renewal support. Explore the treatment options or contact us, and we will guide you to the best method for your skin.

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